| VOL. XVII,
Supplement 1, 2001
|
|
| Proceedings of
the "1 st
International
Workshop on Space Radiation Research and 11 th Annual NASA Space Radiation
Health Investigators’ Workshop", Arona (Italy),
May 27-31, 2000
|
|
| cover
|
|
| Foreword
|
|
| W. Schimmerling (full .pdf file)
|
i |
| Preface
|
|
| R. Cirio, F.A.
Cucinotta, M. Durante (full .pdf file)
|
iii |
| Index
|
|
| General lectures
|
|
| J. Kiefer Space radiation research in the new millenium – from where we come and where we go. (full .pdf file)
|
1 |
| F.A. Cucinotta Once we know all the radiobiology we need to know, how can we use it to predict space radiation risks, and achieve fame and fortune? (full .pdf file)
|
5 |
| G. Kraft What we can learn from heavy ion therapy for radioprotection in space. (full .pdf file)
|
13 |
| E.J. Hall Genomic Instability, Bystander Effect, Cytoplasmic Irradiation and other phenomena that may achieve fame without fortune. (full .pdf file)
|
21 |
| Space Radiation and
Hadrontherapy: a synergistic interaction
|
|
| D.I. Lowenstein BNL Accelerator-Based Radiobiology Facilities. (full .pdf file)
|
26 |
| G.A. Nelson, L.M. Green,
D.S. Gridley, J.O. Archambeau, J.M. Slater Research Activities at the Loma Linda University and Proton Treatment Facility - An overview. (full .pdf file)
|
30 |
| U. Amaldi The Italian hadrontherapy project CNAO (full .pdf file)
|
33 |
| H. Nikjoo, S. Uehara,
I.G. Khvostunov, F.A. Cucinotta, D.T. Goodhead Monte Carlo track structure for radiation biology and space applications. (full .pdf file)
|
38 |
| J. Miller Recent measurements for hadrontherapy and space radiation: nuclear physics. (full .pdf file)
|
45 |
| E.A. Blakely New Measurements for Hadrontherapy and Space Radiation: Biology. (full .pdf file)
|
50 |
| NSCORT session
|
|
| A. Chatterjee, T.H.
Borak Physical and biological studies with protons and HZE particles in a NASA supported research center in radiation health. (full .pdf file)
|
59 |
| Computer codes and
calculations
|
|
| J. Wilson, F.A.
Cucinotta, M.Y. Kim, W. Schimmerling Optimized Shielding for Space Radiation Protection. (full .pdf file)
|
67 |
| A. Ferrari, J. Ranft,
P.R. Sala The FLUKA radiation transport code and its use for space problems. (full .pdf file)
|
72 |
| M.H.Y. Kim, S.A.
Thibeault, J.W. Wilson, L. Heilbronn, R.L. Kiefer, J.A.
Weakley, J.L. Dueber, T. Fogarty, R. Wilkins Radiation Protection Using Martian Surface Materials in Human Exploration of Mars. (full .pdf file)
|
81 |
| L.W. Townsend Overview of active methods for shielding spacecraft from energetic space radiation. (full .pdf file)
|
84 |
| L.S. Pinsky, T.L.
Wilson, A. Ferrari, P. Sala, F. Carminati, R. Brun Development of a space radiation Monte-Carlo computer simulation based on the FLUKA and ROOT codes. (full .pdf file)
|
86 |
| R.C. Singleterry Jr,
J.W. Wilson, J.L. Shinn, R.K. Tripathi, S.A. Thibeault,
A.K. Noor, F.A. Cucinotta, F.F. Badavi, C.K. Chang, G.D.
Qualls, M.S. Clowdsley, M.-H.Y. Kim, J.H. Heinbockel, J.
Norbury, S.R. Blattning, J. Miller, C. Zeitlin, L.H.
Heilbronn Creation and Utilization of a World Wide Web Based Space Radiation Effects Code: SIREST. (full .pdf file)
|
90 |
| M.S. Clowdsley, J.W.
Wilson, M.-H.Y. Kim, R.C. Singleterry, R.K. Tripathi,
J.H. Heinbockel, F.F. Badavi, J.L. Shinn Neutron Environments on the Martian Surface. (full .pdf file)
|
94 |
| U. Schneider, A. Lomax,
N. Lombriser Comparative Treatment Planning using Secondary Cancer Mortality Calculations. (full .pdf file)
|
97 |
| L. Cella, A. Lomax, R.
Miralbell New Techniques in Hadrontherapy: Intensity Modulated Proton Beams. (full .pdf file)
|
100 |
| M. Biaggi, F. Ballarini,
A. Ferrari, A. Ottolenghi, M. Pelliccioni A Monte-Carlo code for a direct estimation of radiation risk. (full .pdf file)
|
103 |
| P.B. Saganti, E.N. Zapp,
J.W. Wilson, F.A. Cucinotta Visual Assessment of the Radiation Distribution in the ISS Lab Module: Visualization in the Human Body. (full .pdf file)
|
106 |
| D. Emfietzoglou, G.
Papamichael, M. Moscovitch Monte-Carlo simulation of charged particle transport in biomatter. (full .pdf file)
|
113 |
| Physical measurements
|
|
| A. Ferrari, A. Mitaroff,
M. Silari A reference radiation facility for dosimetry at flight altitude and in space. (full .pdf file)
|
115 |
| W. Hajdas, A. Zehnder,
L. Adams, P. Buehler, R. Harboe-Sorensen, M. Daum, R.
Nickson, E. Daly, P. Nieminen Proton Irradiation Facility and Space Radiation Monitoring at the Paul Scherrer Institute. (full .pdf file)
|
119 |
| A. Moroni, U.
Abbondanno, C. Agodi, R. Alba, F. Ballarini, G. Bellia,
M. Biaggi, M. Bruno, G. Casini, S. Cavallaro, R.
Cherubini, M. Chiari, M. Colonna, R. Coniglione, M.
D’Agostino, A. Del Zoppo, A. Giussani, F. Gramegna,
C. Maiolino, G.V. Margagliotti, P.F. Mastinu, E. Migneco,
P.M. Milazzo, A. Nannini, A. Ordine, A. Ottolenghi, P.
Piattelli, D. Santonocito, P. Sapienza, G. Vannini, L.
Vannucci, E. Vardaci Nuclear detecting systems at LNL and LNS: foreseen experiments to provide basic data for heavy-ion risk assessment. (full .pdf file)
|
124 |
| T. Berger, M. Hajek, W.
Schöner, M. Fugger, N. Vana, M. Noll, R. Ebner, Y.
Akatov, V. Shurshakov, V. Arkhangelsky Measurement of the Depth Distribution of Average LET and Absorbed Dose Inside a Water-Filled Phantom on Board Space Station MIR. (full .pdf file)
|
128 |
| M.R. Shavers, F.A.
Cucinotta, J. Miller, C. Zeitlin, L. Heilbronn, J.W.
Wilson, R.C. Singleterry Jr. Shielded Heavy-Ion Environment Linear Detector (SHIELD): An Experiment for the Radiation and Technology Demonstration (RTD) Mission. (full .pdf file)
|
131 |
| H. Yasuda, M. Suzuki, K.
Ando, K. Fujitaka Simulation of the low-Earth-orbit dose rates using secondary radiations from the HZE particles at NIRS-HIMAC. (full .pdf file)
|
133 |
| J.C. Sutherland, D.C.
Monteleone, J.G. Trunk The Integrating Ion Imager: A Device for Determining Heavy Ion Doses During Irradiations. (full .pdf file)
|
137 |
| P. Scampoli, M. Casale,
M. Durante, G. Grossi, M. Pugliese, G. Gialanella Cell Inactivation by Beryllium, Boron and Carbon Ions at the Low-energy Irradiation Facility of the Naples University. (full .pdf file)
|
141 |
| J. de Boer, J. Besserer,
M. Moosburger, P. Quicken, P. Bilski, T. Kwiecien, P.
Olko Dosimetry of Low-Energy Protons on the Vertical-Beam Facility at the Munich Accelerator. (full .pdf file)
|
143 |
| M. Fromm, F. Vaginay, D.
Pusset, G. Meesen, A. Chambaudet, A. Poffijn 3-D Confocal Microscopy of Etched Nuclear Tracks in CR-39. (full .pdf file)
|
144 |
| Biophysical models
|
|
| A.A. Edwards RBE of Radiations in Space and the Implication, for Space Travel. (full .pdf file)
|
147 |
| A.L. Ponomarev, F.A.
Cucinotta, R.K. Sachs, D.J. Brenner Monte Carlo Predictions of DNA Fragment-Size Distributions for Large Sizes after HZE Particle Irradiation. (full .pdf file)
|
153 |
| S.B. Curtis, E.G.
Luebeck, W.D. Hazelton, S. H. Moolgavkar The Role of Promotion in Carcinogenesis from Protracted High-LET Exposure. (full .pdf file)
|
157 |
| E. Gudowska-Nowak, A.
Kleczkowski, G. Kraft, E. Nasonova, S. Ritter, M. Scholz Mathematical Models of Radiation-Induced Mitotic Delay: Time Course Analysis and Statistics of Lesions. (full .pdf file)
|
161 |
| R. Katz, F.A. Cucinotta,
M. Fromm, A. Chambaudet Ion-Kill Dosimetry. (full .pdf file)
|
164 |
| H. Yasuda, T. Komiyama,
K. Fujitaka Probability of hippocampus cell hits by high-LET space radiation in a low-Earth-orbit mission (STS-91). (full .pdf file)
|
166 |
| M.V. Lokajic /ek, T. C/echák,
L. Judas, J. Kluson /,
V. Kundrát, K. Prokeš Inactivation of individual cells by divers ions at different LET values. (full .pdf file)
|
170 |
| G. De Angelis, M.
Caldora, M. Santaquilani, R. Scipione, A. Verdecchia Radiation-induced biological effects on crew members: a combined analysis on atmospheric flight personnel. (full .pdf file)
|
173 |
| S. Chauvie, R. Cirio, M.
Donetto, F. Marchetto, C. Peroni A Monte Carlo Model for Cell-Cycle Kinetics in Charged particle Irradiation. (full .pdf file)
|
175 |
| R. Schulte, V.
Bashkirov, S. Shchemelinin, G. Garty, R. Chechik, A.
Breskin Modeling of radiation action based on nanodosimetric event spectra. (full .pdf file)
|
177 |
| R.D. Esposito, M.
Durante, G. Gialanella, G. Grossi, M. Pugliese, P.
Scampoli, T.D. Jones A model of radiation-induced myelopoiesis in space. (full .pdf file)
|
181 |
| In vivo studies
|
|
| A.L. Brooks, S. Bao, K.
Rithidech, W.B. Chrisler, L.A. Couch, L.A. Braby Induction and Repair of HZE Induced Cytogenetic Damage. (full .pdf file)
|
183 |
| A. Becciolini, S.
Porciani, A. Lanini, M. Balzi, P. Faraoni Proposal for biochemical dosimeter for prolonged space flights. (full .pdf file)
|
185 |
| S. Porciani, A. Lanini,
M. Balzi, P. Faraoni, A. Becciolini Polyamines as biochemical indicators of radiation injury. (full .pdf file)
|
187 |
| P.Y. Chang, N. Kanazawa,
L. Lutze-Mann, R. Winegar HZE Particle Radiation Induces Tissue-specific and M53-dependent Mutagenesis in Transgenic Animals. (full .pdf file)
|
189 |
| F. Yatagai, T. Nohmi, M.
Kusakabe, K. Masumura, A. Yoshiki, H. Yamaguchi, T.
Kurobe, K. Kuniya, F. Hanaoka, Y. Yano Mutation Induction by heavy-ion irradiation of gpt D transgenic mice. (full .pdf file)
|
192 |
| F.J. Burns, P. Zhao, G.
Xu, N. Roy, C. Loomis Fibroma Induction in Rat Skin Following Single or Multiple Doses of 1.0 GeV/nucleon 56 Fe Ions from the Brookhaven Alternating Gradient Synchrotron (AGS). (full .pdf file)
|
194 |
| Central nervous system
|
|
| B.M. Rabin, B.
Shukitt-Hale, J.A. Joseph, N. Denissova Effects of exposure to 56 Fe particles on the acquisition of a conditioned place preference in rats. (full .pdf file)
|
196 |
| Cellular and molecular
biology
|
|
| E. Nasonova, S. Ritter,
E. Gudowska-Novak, G. Kraft High-LET-induced chromosomal damage: time-dependent expression. (full .pdf file)
|
198 |
| B.M. Sutherland, P.V.
Bennett, H. Schenk, O. Sidorkina, J. Laval, J. Trunk, D.
Monteleone, J. Sutherland Clustered DNA Damages Induced by High and Low LET Radiation, Including Heavy Ions. (full .pdf file)
|
202 |
| N. Cheong, Z.-C. Zeng,
Y. Wang, G. Iliakis Evidence for factors modulating radiation-induced G2-delay: potential application as radioprotectors. (full .pdf file)
|
205 |
| C. Baumstark-Khan, C.E.
Hellweg, M. Palm, G. Horneck Enhanced Green Fluorescent Protein (EGFP) for Space Radiation Research using Mammalian Cells in the International Space Station. (full .pdf file)
|
210 |
| T. Ohnishi, A.
Takahashi, K. Ohnishi, M. Yonezawa Tumor suppressor p53 response is blunted by low-dose-rate radiation. (full .pdf file)
|
215 |
| S. Brons, B. Jakob, G.
Taucher-Scholz, G. Kraft Heavy ion production of single- and double-strand breaks in plasmid DNA in aqueous solution. (full .pdf file)
|
217 |
| M. Belli, V. Dini, G.
Esposito, P. Micera, O. Sapora, C. Signoretti, G. Simone,
B. Stenerlöw, M.A. Tabocchini DNA fragmentation induced in K562 cells by nitrogen ions. (full .pdf file)
|
219 |
| K. George, H. Wu, V.
Willingham, F.A. Cucinotta The Effect of Space Radiation on the Induction of Chromosome Damage. (full .pdf file)
|
222 |
| T. Kawata, M. Durante,
K. George, Y. Furusawa, E. Gotoh, N. Takai, H. Wu, F.A.
Cucinotta Kineticts of chromatid break repair in G2-human fibroblasts exposed to low- and high-LET radiation. (full .pdf file)
|
226 |
| H. Wu, K. George, V.
Willingham, F.A. Cucinotta Comparison of chromosome aberration frequencies in pre- and post-flight astronaut lymphocytes irradiated in vitro with gamma rays. (full .pdf file)
|
229 |
| A. Francesconi, E. Del
Terra, A. Meli, F.S. Ambesi-Impiombato Standardization of the comet assay technique on FRTLC-5 Cells. (full .pdf file)
|
232 |
| S. Gauny, C. Wiese, A.
Kronenberg Mechanisms of mutagenesis in human cells exposed to 55 MeV protons. (full .pdf file)
|
235 |
| A. Grosovsky, H. Bethel,
K. Parks, L. Ritter, C. Giver, S. Gauny, C. Wiese, A.
Kronenberg Genomic instability in human lymphoid cells exposed to 1 GeV/amu Fe ions. (full .pdf file)
|
238 |
| G. Palumbo, L. Varriale,
V. Paba, A. Sasso, E. Crescenzi, G. Gialanella, G.
Grossi, M.G. Pugliese, P. Scampoli Effect of space radiation on expression of apoptosis-related genes in endometrial cells: a preliminary study. (full .pdf file)
|
241 |
| M.P.J. McNamara, K.A.
Bjornstad, P.Y. Chang, W. Chou, S.J. Lockett, E.A.
Blakely Modulation of Lens Cell Adhesion Molecules by Particle Beams. (full .pdf file)
|
247 |
| Space Radiation Research
in Italy
|
|
| P. Spillantini, F.
Taccetti, P. Papini, L. Rossi, M. Casolino Radiation shielding of astronauts in interplanetary flights: the CREAM surveyor to Mars and the magnetic lens system for a spaceship. (full .pdf file)
|
249 |
| L. Narici, V. Bidoli, M.
Casolino, M.P. De Pascale, G. Furano, I. Modena, A.
Morselli, P. Picozza, E. Reali, R. Sparvoli, S. Licoccia,
P. Romagnoli, E. Traversa, W.G. Sannita, A. Loizzo, A.
Galper, A. Khodarovich, M.G. Korotkov, A. Popov, N.
Vavilov, S. Avdeev, V.P. Salnitskii, O.I. Shevchenko,
V.P. Petrov, K.A. Trukhanov, M. Boezio, W. Bonvicini, A.
Vacchi, N. Zampa, R. Battiston, G. Mazzenga, M. Ricci, P.
Spillantini, G. Castellini, P. Carlson, C. Fuglesang The ALTEA facility on the International Space Station. (full .pdf file)
|
255 |
| G. De Angelis, M.
Caldora, M. Santaquilani, R. Scipione, A. Verdecchia Radiation exposure of civilian airline crew members and associated biological effects due to the atmospheric ionizing radiation environment. (full .pdf file)
|
258 |
| E. Del Terra, A.
Francesconi, A. Meli, F.S. Ambesi-Impiombato Radiation-dependent apoptosis on cultured thyroid cells. (full .pdf file)
|
261 |
| P. Mosesso, M. Schuber,
D. Seibt, C. Schmitz, M. Fiore, A. Schinoppi, S. Penna,
F. Palitti X-ray-induced chromosome aberrations in human lymphocytes in vitro are potentiated under simulated microgravity conditions (clinostat). (full .pdf file)
|
264 |
| G. Angelini, P. Ragni,
D. Esposito, P. Giardi, M.L. Pompili, R. Moscardelli,
M.T. Giardi A device to study the effect of space radiation on photosyntetic organisms. (full .pdf file)
|
267 |
| M. Durante Influence of the shielding on the space radiation biological effectiveness. (full .pdf file)
|
269 |
| A. Ottolenghi, F.
Ballarini, M. Biaggi Mechanistic bases for modelling space radiation risk and planning radiation protection of astronauts. (full .pdf file)
|
272 |
| M. Belli An overview of recent charged-particle radiation biology in Italy. (full .pdf file)
|
278 |
| Radiation Research for the
International Space Station
|
|
| G. Reitz European Dosimetry Activities for the ISS. (full .pdf file)
|
283 |
| G.D. Badhwar Radiation Measurements on the International Space Station. (full .pdf file)
|
287 |
| K. Ando High LET radiobiology at NIRS-current status and future plan. (full .pdf file) |
294 |