Highlights
- •Small animal Cerenkov luminescence imaging.
- •Cerenkov luminescence tomography.
- •Radioluminescence imaging.
- •Human Cerenkov imaging.
Abstract
The main goals of this review is to provide an up-to-date account of the different
uses of Cerenkov radiation (CR) and radioluminescence imaging for pre-clinical small
animal imaging. We will focus on new emerging applications such as the use of Cerenkov
imaging for monitoring radionuclide and external radiotherapy in humans. Another novel
application that will be described is the monitoring of radiochemical synthesis using
microfluidic chips.
Several pre-clinical aspects of CR will be discussed such as the development of 3D
reconstruction methods for Cerenkov images and the use of CR as excitation source
for nanoparticles or for endoscopic imaging.
We will also include a discussion on radioluminescence imaging that is a more general
method than Cerenkov imaging for the detection using optical methods of alpha and
gamma emitters.
Keywords
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Article info
Publication history
Published online: December 31, 2014
Accepted:
December 13,
2014
Received in revised form:
December 11,
2014
Received:
July 28,
2014
Identification
Copyright
© 2014 Associazione Italiana di Fisica Medica. Published by Elsevier Inc. All rights reserved.
