Highlights
- •A low-cost model to track markers from CBCT projections.
- •Edge detection algorithms with filtering and discreet cosine transforms.
- •Capable of processing Varian and Elekta images.
- •Data collected for 12 prostate patients and 1 lung patient.
- •Model accuracy dependant on the localisation of excessive bony anatomy.
Abstract
Purpose
To construct a method and software to track gold seed implants in prostate and lung
patients undergoing radiotherapy using CBCT image projections.
Methods
A mathematical model was developed in the MatLab (Mathworks, Natick, USA) environment
which uses a combination of discreet cosine transforms and filtering to enhance several
edge detection methods for identifying and tracking gold seed fiducial markers in
images obtained from Varian (Varian Medical Systems, Palo Alto, USA) and Elekta (Kungstensgatan,
Sweden) CBCT projections.
Results
Organ motion was captured for 16 prostate patients and 1 lung patient.
Conclusion
Image enhancement and edge detection is capable of automatically tracking markers
for up to 98% (Varian) and 79% (Elekta) of CBCT projections for prostate and lung
markers however inclusion of excessive bony anatomy (LT and RT LAT) inhibit the ability
of the model to accurate determine marker location.
Keywords
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References
- Dosimetric analysis of patient setup and mechanical uncertainties in RapidArc prostate treatments.Phys Med. 2013; 29: 573-574
- Cancer in Australia: an overview 2014. Cancer series no. 90. CAN 88. Canberra.2014
- Multi-institutional clinical experience with the Calypso system in localization and continuous, real-time monitoring of the prostate gland during external radiotherapy.Int J Radiat Oncol Biol Phys. 2007; 67: 1088-1098
- Site-specific volumetric analysis of lung tumour motion.Phys Med Biol. 2010; 55: 3325-3337
- Real-time 3D internal marker tracking during arc radiotherapy by the use of combined MV–kV imaging.Phys Med Biol. 2008; 53: 7197-7213
- A fiducial detection algorithm for real-time image guided IMRT based on simultaneous MV and kV imaging.Med Phys. 2008; 35: 3554-3564
- Use of MV and kV imager correlation for maintaining continuous real-time 3D internal marker tracking during beam interruptions.Phys Med Biol. 2009; 54: 89-103
- Implementation of fiducial-based image registration in the cyberknife robotic system.Med Dosim. 2008; 33: 156-160
- 3-D fiducial motion tracking using limited MV projections in arc therapy.Med Phys. 2011; 38: 3222-3231
- Kilovoltage intrafraction monitoring for prostate intensity modulated arc therapy: first clinical results.Int J Radiat Oncol Biol Phys. 2012; 84: 655-661
- Stochastic triangulation for prostate positioning during radiotherapy using short CBCT arcs.Radiother Oncol. 2013; 106: 241-249
- Automatic prostate tracking and motion assessment in volumetric modulated arc therapy with an electronic portal imaging device.Int J Radiat Oncol Biol Phys. 2013; 86: 762-768
- Speed and amplitude of lung tumor motion precisely detected in four-dimensional setup and in real-time tumor-tracking radiotherapy.Int J Radiat Oncol Biol Phys. 2006; 64: 1229-1236
- Fluoroscopic tracking of multiple implanted fiducial markers using multiple object tracking.Phys Med Biol. 2007; 52: 4081-4098
- Evaluation of ultrasound-based prostate localization for image-guided radiotherapy.Int J Radiat Oncol Biol Phys. 2003; 57: 635-664
- Observations on real-time prostate gland motion using electromagnetic tracking.Int J Radiat Oncol Biol Phys. 2008; 71: 1084-1090
- Tracking accuracy of a real-time fiducial tracking system for patient positioning and monitoring in radiation therapy.Int J Radiat Oncol Biol Phys. 2010; 78: 1227-1234
- A method to estimate mean position, motion magnitude, motion correlation, and trajectory of a tumor from cone-beam CT projections for image-guided radiotherapy.Int J Radiat Oncol Biol Phys. 2008; 72: 1587-1596
- Using cone-beam CT projection images to estimate the average and complete trajectory of a fiducial marker moving with respiration.Phys Med Biol. 2010; 55: 7439-7452
- A method for robust segmentation of arbitrarily shaped radiopaque structures in cone-beam CT projections.Med Phys. 2011; 38: 2151-2156
- Robust automatic segmentation of multiple implanted cylindrical gold fiducial markers in cone-beam CT projections.Med Phys. 2011; 38: 6351-6361
- Measurement of inter and intra fraction organ motion in radiotherapy using cone beam CT projection images.Phys Med Biol. 2008; 53: 1087-1098
- Intra-fraction prostate displacement in radiotherapy estimated from pre- and post-treatment imaging of patients with implanted fiducial markers.Radiother Oncol. 2010; 95: 191-197
- Monitoring tumor motion with on-line mega-voltage cone-beam computed tomography imaging in a cine mode.Phys Med Biol. 2008; 53: 823-836
- Monte Carlo modeling of converging small-field contrast-enhanced radiotherapy of prostate.Phys Med. 2013; 29: 493-499
- The use of the active breathing coordinator throughout radical non-small-cell lung cancer (NSCLC) radiotherapy.Int J Radiat Oncol Biol Phys. 2011; 81: 369-375
- Evaluation of integrated respiratory gating systems on a Novalis Tx system.J Appl Clin Med Phys. 2011; 12: 71-79
- Expanding the use of real-time electromagnetic tracking in radiation oncology.J Appl Clin Med Phys. 2011; 12: 34-49
Article info
Publication history
Published online: January 23, 2015
Accepted:
January 7,
2015
Received in revised form:
December 5,
2014
Received:
March 28,
2014
Identification
Copyright
© 2015 Published by Elsevier Inc. All rights reserved.
