Highlights
- •The effect of gantry rotation speed on 4D-CBCT images for liver SBRT was studied.
- •The signal- and contrast-to-noise ratios and structural similarity were measured.
- •The fiducial marker positions were compared with setup and reference values.
- •The gantry rotation speed was found to affect image quality significantly.
- •Gantry rotation speeds of 67 and 85° min−1 were optimal.
Abstract
In this study, qualities of 4D cone-beam CT (CBCT) images obtained using various gantry
rotation speeds (GRSs) for liver stereotactic body radiation therapy (SBRT) with fiducial
markers were quantitatively evaluated. Abdominal phantom containing a fiducial marker
was moved along a sinusoidal waveform, and 4D-CBCT images were acquired with GRSs
of 50–200° min−1. We obtained the 4D-CBCT projection data from six patients who underwent liver SBRT
and generated 4D-CBCT images at GRSs of 67–200° min−1, by varying the number of projection data points. The image quality was evaluated
based on the signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and structural
similarity index (SSIM). The fiducial marker positions with different GRSs were compared
with the setup values and a reference position in the phantom and clinical studies,
respectively. The root mean square errors (RMSEs) were calculated relative to the
reference positions. In the phantom study, the mean SNR, CNR, and SSIM decreased from
37.6 to 10.1, from 39.8 to 10.1, and from 0.9 to 0.7, respectively, as the GRS increased
from 50 to 200° min−1. The fiducial marker positions were within 2.0 mm at all GRSs. Similarly, in the
clinical study, the mean SNR, CNR, and SSIM decreased from 50.4 to 13.7, from 24.2
to 6.0, and from 0.92 to 0.73, respectively. The mean RMSEs were 2.0, 2.1, and 3.6 mm
for the GRSs of 67, 100, and 200° min−1, respectively. We conclude that GRSs of 67 and 85° min−1 yield images of acceptable quality for 4D-CBCT in liver SBRT with fiducial markers.
Keywords
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Article info
Publication history
Accepted:
November 26,
2017
Received in revised form:
November 24,
2017
Received:
September 5,
2017
Identification
Copyright
© 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
