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Original paper| Volume 64, P54-68, August 2019

Optimization of Phase Space files from clinical linear accelerators

  • Author Footnotes
    1 Both authors contributed equally to the work and are thus listed in alphabetic order.
    Juliana Cristina Martins
    Correspondence
    Corresponding author.
    Footnotes
    1 Both authors contributed equally to the work and are thus listed in alphabetic order.
    Affiliations
    Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching b. München, Germany
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  • Author Footnotes
    1 Both authors contributed equally to the work and are thus listed in alphabetic order.
    ,
    Author Footnotes
    2 Present Address: Max Planck Institute of Neurobiology, Am Klopferspitz 18, 82152 Martinsried, Germany.
    Rangoli Saxena
    Footnotes
    1 Both authors contributed equally to the work and are thus listed in alphabetic order.
    2 Present Address: Max Planck Institute of Neurobiology, Am Klopferspitz 18, 82152 Martinsried, Germany.
    Affiliations
    Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching b. München, Germany
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  • Sebastian Neppl
    Affiliations
    Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße15, 81377 Munich, Germany
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  • Abdulaziz Alhazmi
    Affiliations
    Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching b. München, Germany
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  • Michael Reiner
    Affiliations
    Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße15, 81377 Munich, Germany
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  • Author Footnotes
    3 Present Address: Departamento de Fisica, Universidad Nacional de Colombia, Carrera 30 No. 45 03, 111321 Bogota, Colombia.
    Stella Veloza
    Footnotes
    3 Present Address: Departamento de Fisica, Universidad Nacional de Colombia, Carrera 30 No. 45 03, 111321 Bogota, Colombia.
    Affiliations
    Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching b. München, Germany
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  • Claus Belka
    Affiliations
    Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße15, 81377 Munich, Germany

    German Cancer Consortium (DKTK), Pettenkoferstraße 8a, 80336 Munich, Germany
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  • Katia Parodi
    Affiliations
    Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching b. München, Germany
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  • Author Footnotes
    1 Both authors contributed equally to the work and are thus listed in alphabetic order.
    2 Present Address: Max Planck Institute of Neurobiology, Am Klopferspitz 18, 82152 Martinsried, Germany.
    3 Present Address: Departamento de Fisica, Universidad Nacional de Colombia, Carrera 30 No. 45 03, 111321 Bogota, Colombia.

      Highlights

      • A general methodology for optimization of existing Phase Space files was developed.
      • A linear relationship between beam divergence and lateral profiles was obtained.
      • Optimization factors for particles’ energy and direction have been identified.
      • Remarkable improvement in the agreement among measured and simulated data observed.
      • Viable alternative in absence of geometric information and validated Phase Space.

      Abstract

      This work proposes a methodology to produce an optimized phase-space (PhSp) for the Elekta Synergy linac by tuning the energy and direction of particles inside the 6-MV Elekta Precise PhSp, provided by the International Atomic Energy Agency (IAEA), for Monte Carlo (MC) simulations. First, the energies of the particles emerging from the original PhSp were increased by different factors, producing new PhSps. Percentage depth dose (PDD) profiles were simulated and compared to measured data from a Synergy linac for 6-MV photon beam. This process was repeated until a minimum difference was reached. Particles’ directions were then manipulated following identified correlations to lateral profiles, resulting in two distinct perturbation factors based on inline and crossline profiles. Both factors were merged into one single optimal factor. For energy optimization, an increase of 0.32 MeV applied to all particles inside the original PhSp, but to 0.511 MeV annihilation photons, provided the best results. The direction optimization factor was the combination of the individual factors for inline (0.605%) and crossline (0.051%). The agreement between measured and simulated profiles, when using the optimized PhSp, improved considerably in comparison to simulations performed with the original IAEA PhSp. For all fields and depths analyzed, the discrepancies for PDD, inline and crossline profiles dropped from 11.2%, 15.7% and 27.5% to under 1.4%, 4.7% and 13.2%, respectively. The optimized PhSp should not replace the full linac modelling, however it offers an alternative for MC dose calculations when neither geometric details nor validated IAEA PhSp are available to the user.

      Keywords

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