Preclinical trials involving mice are now a standard component of research in radiation
oncology and radiobiology. Image-guided irradiations of small animals utilize small
field sizes (1 × 1 cm2), necessitating accurate and precise real-time dosimeters with high spatial resolution
capabilities for treatment verification and quality assurance [1]. Plastic scintillation
detectors (PSDs) are commonly used in optical fibre-based dosimetry in this field
due to the small geometry and near water-equivalence of the active volume. However,
the low signal output of these detectors can lead to uncertainties which affect the
precision of low dose measurements and thus dosimetric QA.
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